I guess most settings are default, I also use both Avira and Bitdefender engines.
No exclusions on the trustlist and realtime scanner is ON. The scan on opening files is OFF, but as far as I know that is default. Because all files are scanned while downloading/copying/at creation.
I have downloaded and work with the 32bit versions, although I tested it on the 64bit 1.3.0 beta3 too.
No error/alarm messages while downloading these files, not while opening the zip-files and also not when I manually scan these files.